Warning! The following contains spoilers from My Hero Academia. You have been warned.
We learned in recent chapters that the students of Class 1A and Class 1B tried to sedate Gigantomachia before he could reach Tomura Shigaraki. Now, it looks like that plan failed with dire consequences. After escaping the clutches of the students, Gigantomachia switched into a new form before mopping the floor with the surrounding superheroes. Fortunately, the students were evacuated with minor injuries, but the superheroes were defeated and possibly killed by the giant supervillain. Just as I predicted, once Gigantomachia entered the fight, the battle at the mansion became a one-sided massacre.
With the superheroes and students dealt with, Gigantomachia continued his rampage across Japan as he made his way toward Shigaraki. By my count, over twenty cities are in the process of being demolished by both Gigantomachia and the remnants of the Paranormal Liberation Front. By the time Gigantomachia and the Paranormal Liberation Front reach Shigaraki, half of Japan will be in ruins.
One must consider the long term consequences of Gigantomachia’s rampage. Almost every superhero in Japan was involved in the battles against the Paranormal Liberation Front. As a result, many cities were defenseless. The superheroes gambled everything they had in this war and it looks like they are losing big time. Even if they defeat or capture Shigaraki, Gigantomachia can track his scent no matter where they take him, even Tartarus Prison. Worse, the public’s trust in the superhero community was already badly shaken after All Might’s retirement. With so many cities destroyed and lives lost, the public will likely never trust the superhero community again as it is now.
As for the surviving students, I believe their self-confidence in their capabilities as superheroes will be very badly shaken. They used all of their training and best efforts to bring Gigantomachia down and failed miserably. Now, a lot of superheroes are dead, leaving a growing power vacuum in the superhero society. The aftermath of this battle will likely motivate the students to fill the void left by the dead superheroes.