One of the most infamous supervillains would have to be Doomsday because he was the one who killed Superman. The chaos, death, and destruction he leaves in his wake certainly earn him his name. His duel with Superman was easily one of the most epic hero/villain battles I have ever seen. This is what happens when an unstoppable force meets an immovable object, Doomsday being the unstoppable force and Superman being the immovable object. In addition, I like Doomsday’s ability to regenerate from any injury and adapt to it so that he could not be beaten the same way twice. This power easily makes him one of Superman’s deadliest enemies because he keeps coming back stronger and more durable than before.